Last October I posted here about what apps were incompatible with High Sierra.
I need to add that Filemaker Pro 11 is completely unusable. It crashes whenever you do anything. (And according to a comment below FileMaker 12 does not work either.)
If you rely on Filemaker Pro, and you want to upgrade to High Sierra, Fielmaker suggest you upgrade to Filemaker Pro 14. I cant’ vouch for version 12 or 13, but 11 is very unstable.
It seems that there are some pretty significant under the hood changes in High Sierra. The list of incompatible Apps is higher than any previous release of OS-X, including Apple’s Final Cut Pro, Motion, Compressor,Logic Pro X and MainStage which all needed to be upgraded.